- The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease.
- Scaramozza, Annarita <1982>
Subject
- BIO/16 Anatomia umana
Description
- Skeletal muscle possesses the remarkable capacity to complete a rapid and extensive regeneration, even following severe damage. The regenerative ability of skeletal muscle relies on Satellite Cells (SCs), a population of muscle specific adult stem cells. However, during aging or under several pathological conditions, the ability of skeletal muscle to fully regenerated is compromised. Here, a morphological and molecular study on SCs from patients affected by ALS is described. Moreover, the role of the cell cycle regulator P16Ink4a during skeletal muscle regeneration and aging has been investigated.
Date
- 2012-01-16
Type
- Doctoral Thesis
- PeerReviewed
Format
- application/pdf
Identifier
urn:nbn:it:unibo-4488
Scaramozza, Annarita (2012) The regulation of Satellite Cells during skeletal muscle regeneration and neuromuscular disease., [Dissertation thesis], Alma Mater Studiorum Università di Bologna. Dottorato di ricerca in Scienze biomediche: progetto n. 5 "Scienze morfologiche umane e molecolari"